Molecular Models of Rosmarinic Acid and DPPH
نویسندگان
چکیده
منابع مشابه
Rosmarinic Acid--Pharmaceutical and Clinical Aspects.
The biosynthesis and biotechnological production of Rosmarinic acid, a phenolic ester that is widespread in the plant kingdom, has been widely investigated. This compound has shown many remarkable biological and pharmacological activities, which have led to its pharmaceutical and analytical development, as well as clinical studies, which are summarized and analyzed here for the first time. This...
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Prunella vulgaris L., commonly known as "self-heal" or "heal-all," is a perennial herb with a long history of medicinal use. Phenylalanine ammonia-lyase (PAL), cinnamate 4-hydroxylase (C4H), and 4-coumarate:coenzyme-A (CoA) ligase (4CL) are important enzymes in the phenylpropanoid pathway and in the accumulation of rosmarinic acid (RA), which is a major secondary metabolite in P. vulgaris. In t...
متن کاملMetabolic modeling of Rosmarinic acid biosynthetic pathway
Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllacticacid. It is commonly found in Coleus blumei, Salvia officinalis, Melissa officinalis and Rosmarinus officinalis. The biosynthesis of RA starts with precursor molecules L-phenylalanine and L-tyrosine. Simulation of RA biosynthetic pathway was done using Gepasi Software, includes the reaction kinetics of each step of t...
متن کاملBiogenesis of rosmarinic acid in Mentha.
The biogenesis of rosmarinic acid (alpha-O-caffeoyl-3,4-dihydroxyphenyl-lactic acid), the second most common ester of caffeic acid in the plant kingdom, was studied in Mentha arvense and Mentha piperita. Administration of (14)C-labelled compounds showed that, whereas the caffeoyl moiety was formed from phenylalanine via cinnamic acid and p-coumaric acid, the 3,4-dihydroxyphenyl-lactic acid moie...
متن کاملCaffeic acid oligomers such as rosmarinic acid and lithos-
permic acid B (LAB) are distributed in plants of Labiatae and Boraginaceae. Among these oligomers, LAB, the caffeic acid tetramer, has a variety of attractive pharmacological activities such as antioxidant and radical scavenging, improvement of renal disease, hypotensive, improvement of myocardial infarction, amplification of beating of myocardial muscles, anti-hepatitis, and aldose reductase i...
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ژورنال
عنوان ژورنال: Journal of Chemical Education
سال: 2007
ISSN: 0021-9584,1938-1328
DOI: 10.1021/ed084p1496